HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22732010, compound → HCID 22732055, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22732010 | HCID 22732010 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22732055 | HCID 22732055 | 96% |
Reaction Steps
4-Bromo-2-[(tetrahydropyran4-yl)amino]-phenylacetaldehyde, dimethyl acetal (522 mg, 1.516 mmol) was dissolved in 20 ml of 1M HCl in methanol. The solution was refluxed for 2 hrs and the solvent evaporated to give the title compound (407 mg, 96%) as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716837B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-c5eac003892d4a54995cba4ea9e17bbe |
| Source note | uspto-grants-2004_04 |