HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 9925480, compound → 6-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 9925480 | HCID 9925480 | — |
| Reactant | HCID 10131267 | HCID 10131267 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 6-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 10130559 | — |
Reaction Steps
6-[N-Methyl-1,2,5,6-tetrahydropyridin-4-yl]-1-isopropyl-indole : from 6-[4-Hydroxy-1-methyl-piperidin-4-yl]-1-isopropyl-indole (20 mg, 0.0735 mmol) in 0.1 ml of TFA and 1 ml of THF at 60-64° C. Yield 4.8 mg (26%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716837B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-d5d20d774d204093aa8aeb7165fe83a1 |
| Source note | uspto-grants-2004_04 |