HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1-{3-[3-(benzyloxy)phenyl]propyl)-1H-imidazol-2-yl)-1-ethanol → 3-{3-[2-(2-hydroxyethyl)-1H-imidazol-1-yl]propyl}phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1-{3-[3-(benzyloxy)phenyl]propyl)-1H-imidazol-2-yl)-1-ethanol | HCID 22733373 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Product | 3-{3-[2-(2-hydroxyethyl)-1H-imidazol-1-yl]propyl}phenol | HCID 22733355 | 95.4% |
Reaction Steps
Using 2-(1-{3-[3-(benzyloxy)phenyl]propyl)-1H-imidazol-2-yl)-1-ethanol (2.42 g) and 10% palladium carbon (0.24 g), the same reaction as Reference Example 11-(v) was carried out to yield the titled compound (1.69 g) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716863B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-efc05f0e23214bf391183e3a876b8e22 |
| Source note | uspto-grants-2004_04 |