HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-{1-[4-(4-benzyloxyphenyl)butyl]-1H-imidazol-2-yl}-1,2-propanediol → 3-{1-[4-(4-hydroxyphenyl)butyl]-1H-imidazol-2-yl)-1,2-propanediol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-{1-[4-(4-benzyloxyphenyl)butyl]-1H-imidazol-2-yl}-1,2-propanediol | HCID 22733380 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Product | 3-{1-[4-(4-hydroxyphenyl)butyl]-1H-imidazol-2-yl)-1,2-propanediol | HCID 12109872 | 98.6% |
Reaction Steps
Using 3-{1-[4-(4-benzyloxyphenyl)butyl]-1H-imidazol-2-yl}-1,2-propanediol (1.22 g) and 10% palladium carbon (0.18 g), the same reaction as Reference Example 11-(v) was carried out to yield the titled compound (0.918 g) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06716863B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-b40fbed80b3c44e38dc40df602416872 |
| Source note | uspto-grants-2004_04 |