2-Bromopyridine → HCID 21305229, compound

HRID 2084534Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[CH3:8][C:9]([CH3:33])([CH3:32])[C@H:10]([NH:19][C:20](=[O:31])[C@@H:21]([CH2:26][N:27]([CH:29]=[O:30])[OH:28])[CH2:22][CH2:23][CH2:24][CH3:25])[C:11](C1N(C)C=CN=1)=[O:12]>>[CH3:32][C:9]([CH3:8])([CH3:33])[C@H:10]([NH:19][C:20](=[O:31])[C@@H:21]([CH2:26][N:27]([CH:29]=[O:30])[OH:28])[CH2:22][CH2:23][CH2:24][CH3:25])[C:11]([C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1)=[O:12]

Participants

Reactant 2

HCID 79732-Bromopyridine

HCID 21305228HCID 21305228, compound

Product 1

HCID 21305229HCID 21305229, compound

Procedure

The title compound was prepared from 2-bromopyridine as outlined in Scheme 2, in an analogous manner to 2(R)-[(N-formyl-N-hydroxyamino)-methyl]-hexanoic acid-[2,2-dimethyl-1(S)-(1-methyl-1H-imidazole-2-carbonyl)-propyl]-amide. The relevant spectroscopic data are described below.

Sources & evidence

ORD record: ord-90823ecb0a894c8dbc4607b3e0ebb50c
Source dataset: uspto-grants-2004_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06716878B1

Reaction notes

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