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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2084539Generated: October 29, 2026

Hydrochloric Acid → HCID 136388368, compound

https://huagongshe.com/reaction/2084539

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 60077773HCID 60077773—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 136388368HCID 136388368—

Reaction Steps

(1(S)-tert-Butyl-2-oxo-3-pyridin-2-yl-propyl)-carbamic acid tert-butyl ester (300 mg, 1.0 mmol), was dissolved in dioxane saturated with HCl (20 mL) and the reaction mixture stirred at room temperature for 2 hours. The mixture was then concentrated in vacuo to give the title compound as a yellow solid (0.37 g) which was used in Step C without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06716878B1
Source datasetuspto-grants-2004_04
ORD IDord-9800897a7b3f4d61b03359d8b0e491c9
Source noteuspto-grants-2004_04