Pyridine → Diethyl 1,4-dihydro-2-methyl-4-(3-nitrophenyl)-6-(4-nitrophenyl)-3,5-pyridinedicarboxylate

HRID 208462Notes

Reaction equation

HRID 208462 reaction equation
[CH2:56]([Cl:57])[Cl:58].[F:1][C:2]([F:3])([F:4])[C:5]([O:6][C:7](=[O:8])[C:9]([F:10])([F:11])[F:12])=[O:13].[OH:20][C:21]1([c:47]2[cH:48][cH:49][c:50]([N+:53](=[O:54])[O-:55])[cH:51][cH:52]2)[NH:22][C:23]([CH3:46])=[C:24]([C:41](=[O:42])[O:43][CH2:44][CH3:45])[CH:25]([c:32]2[cH:33][c:34]([N+:38](=[O:39])[O-:40])[cH:35][cH:36][cH:37]2)[CH:26]1[C:27](=[O:28])[O:29][CH2:30][CH3:31].[cH:14]1[cH:15][cH:16][n:17][cH:18][cH:19]1>>[C:21]1([c:47]2[cH:48][cH:49][c:50]([N+:53](=[O:54])[O-:55])[cH:51][cH:52]2)=[C:26]([C:27](=[O:28])[O:29][CH2:30][CH3:31])[CH:25]([c:32]2[cH:33][c:34]([N+:38](=[O:39])[O-:40])[cH:35][cH:36][cH:37]2)[C:24]([C:41](=[O:42])[O:43][CH2:44][CH3:45])=[C:23]([CH3:46])[NH:22]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 9845Trifluoroacetic anhydrideHCID 20189315Diethyl 1,2,3,4-tetrahydro-2-hydroxy-6-methyl-4-(3-nitrophenyl)-2-(4-nitrophenyl)-3,5-pyridinedicarboxylate

Product 1

HCID 20189318Diethyl 1,4-dihydro-2-methyl-4-(3-nitrophenyl)-6-(4-nitrophenyl)-3,5-pyridinedicarboxylate

Sources & evidence

ORD record
ord-f133e6c5580c4c7e875ceb21746dc18a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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