Chloroform → HCID 131724400, compound

HRID 2084695Notes

Reaction equation

HRID 2084695 reaction equation
C(Cl)(Cl)Cl.[C:5]([C:7]1[C:8](=[C:15]([C:18]#[N:19])[C:16]#[N:17])[O:9][C:10]([CH3:14])([CH3:13])[C:11]=1[CH3:12])#[N:6].[C:20]([SiH2:24][O:25][C:26]([CH3:52])([CH3:51])[CH:27]1[CH2:32][O:31][C:30]2=[C:33]([CH:38]=[CH:39][C:40]3[CH:45]=[CH:44][C:43]([N:46]([CH2:49][CH3:50])[CH2:47][CH3:48])=[CH:42][CH:41]=3)[S:34][C:35]([CH:36]=O)=[C:29]2[O:28]1)([CH3:23])([CH3:22])[CH3:21]>C(N(CC)CC)C>[C:20]([SiH2:24][O:25][C:26]([CH3:51])([CH3:52])[CH:27]1[CH2:32][O:31][C:30]2=[C:33]([CH:38]=[CH:39][C:40]3[CH:41]=[CH:42][C:43]([N:46]([CH2:49][CH3:50])[CH2:47][CH3:48])=[CH:44][CH:45]=3)[S:34][C:35]([CH:36]=[CH:12][C:11]3[C:10]([CH3:13])([CH3:14])[O:9][C:8](=[C:15]([C:16]#[N:17])[C:18]#[N:19])[C:7]=3[C:5]#[N:6])=[C:29]2[O:28]1)([CH3:23])([CH3:22])[CH3:21]

Participants

5

Reactant 3

HCID 6212ChloroformHCID 99903452-[3-Cyano-4,5,5-trimethylfuran-2(5H)-ylidene]malononitrileHCID 131724398HCID 131724398, compound

Product 1

HCID 131724400HCID 131724400, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

20 mL of anhydrous chloroform was added to 0.318 g (0.0016 mole) of 2-(3-cyano-4,5,5-trimethyl-5H-furan-2-ylidene)-malononitrile, and 0.640 g (0.00131 mole) of 5. Once in solution, 10 mg of triethylamine were added and the reaction mixture was stirred at room temperature for 12 h. The solvent was removed under reduced pressure. The compound was purified on a silica column with a hexane/ethyl acetate mobile phase.

Workup

  1. customThe solvent was removed under reduced pressure
  2. customThe compound was purified on a silica column with a hexane/ethyl acetate mobile phase

Sources & evidence

ORD record
ord-512945b2203a4d7e8c739142aac16225
Source dataset
uspto-grants-2004_04
Patent number
US06716995B2

Reaction notes

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