HCID 22728659, compound → HCID 22728640, compound

HRID 2084998Notes

Reaction equation

HRID 2084998 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[CH:12]=[C:13]([CH:17]=[CH:18][CH:19]=2)[C:14]([OH:16])=[O:15])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[CH:12]=[C:13]([CH:17]=[CH:18][CH:19]=2)[C:14]([OH:16])=[O:15])=[CH:6][CH:5]=1

Participants

4

Reactant 1

HCID 22728659HCID 22728659, compound

Product 1

HCID 22728640HCID 22728640, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of 3-[(4-nitrophenyl)thio]benzoic acid (11.2 g, 40.7 mmol) and 10% Pd/C (0.5 g) in ethanol (250 mL) was hydrogenated at atmospheric temperature and pressure for 24 h. The mixture was filtered through Celite and concentrated in vacuo to give the required aniline as a solid.

Workup

  1. filtrationThe mixture was filtered through Celite
  2. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-5a8a838edbbd4fae980a0442c3976003
Source dataset
uspto-grants-2004_04
Patent number
US06719520B2

Reaction notes

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