Potassium Carbonate → HCID 60077941, compound

HRID 2085177Notes

Reaction equation

[OH:1][C:2]1[C:10]2[CH:9]=[C:8]([C:11]3[S:12][C:13]([CH3:16])=[N:14][N:15]=3)[O:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.S(C1C=CC([N+]([O-])=O)=CC=1)(O[CH2:21][C@H:22]1[O:24][CH2:23]1)(=O)=O.C(=O)([O-])[O-].[K+].[K+]>>[CH2:21]([O:1][C:2]1[C:10]2[CH:9]=[C:8]([C:11]3[S:12][C:13]([CH3:16])=[N:14][N:15]=3)[O:7][C:6]=2[CH:5]=[CH:4][CH:3]=1)[C@H:22]1[O:24][CH2:23]1

Participants

Reactant 3

HCID 11430Potassium Carbonate

HCID 10868995(S)-(+)-Glycidyl-4-nitrobenzoate

HCID 135794319HCID 135794319, compound

Product 1

HCID 60077941HCID 60077941, compoundYield 74.9%

Procedure

By the reactions in the same manner as in Starting Material Synthesis Example 1 using 2-(4-hydroxybenzo(b)furan-2-yl)-5-methyl-1,3,4-thiadiazole (1.1 g), (S)-glycidyl nosylate (1.2 g) and potassium carbonate (3.0 g), the title compound (1.0 g) was obtained as yellow crystals.

Sources & evidence

ORD record: ord-6981c4cac5f94786b6bd93f14df38820
Source dataset: uspto-grants-2004_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06720320B2

Reaction notes

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