Ethylamine → HCID 69497811, compound

HRID 2085220Notes

Reaction equation

HRID 2085220 reaction equation
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][CH:14]=[CH:13][C:4]=1[CH:5]=[C:6]1[C:10](=[O:11])O[C:8]([CH3:12])=[N:7]1.[CH2:17]([NH2:19])[CH3:18].C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH2:17]([N:19]1[C:10](=[O:11])[C:6](=[CH:5][C:4]2[CH:13]=[CH:14][CH:15]=[CH:16][C:3]=2[O:2][CH3:1])[N:7]=[C:8]1[CH3:12])[CH3:18]

Participants

5

Reactant 3

HCID 6341EthylamineHCID 11430Potassium CarbonateHCID 361416HCID 361416, compound

Product 1

HCID 69497811HCID 69497811, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
80 °C

Procedure

4-(2′-Methoxybenzylidene)-2-methyl-4H-oxazol-5-one (5 g) was dissolved in ethanol (100 ml) and an aqueous ethylamine solution (15 ml) and potassium carbonate (7 g) were added thereto. The mixture was heated at 80° C. for 5 hr. After cooling, the solvent was evaporated under reduced pressure and the precipitated yellow crystals were collected by filtration to give the title compound (1.2 g).

Workup

  1. temperatureAfter cooling
  2. customthe solvent was evaporated under reduced pressure
  3. filtrationthe precipitated yellow crystals were collected by filtration

Sources & evidence

ORD record
ord-6313de3a7c274c92a5f9b6961bc197bc
Source dataset
uspto-grants-2004_04
Patent number
US06720320B2

Reaction notes

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