Salicylaldehyde → alpha-(2'-Hydroxybenzylidene)-gamma-valerolactone

HRID 2085231Notes

Reaction equation

HRID 2085231 reaction equation
[CH:1](=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[C:10]1(=[O:16])[O:15][CH:13]([CH3:14])[CH2:12][CH2:11]1>C1(C)C=CC=CC=1>[OH:4][C:3]1[CH:5]=[CH:6][CH:7]=[CH:8][C:2]=1[CH:1]=[C:11]1[CH2:12][CH:13]([CH3:14])[O:15][C:10]1=[O:16]

Participants

4

Reactant 2

HCID 6998SalicylaldehydeHCID 7921Gamma-Valerolactone

Product 1

HCID 69497707alpha-(2'-Hydroxybenzylidene)-gamma-valerolactoneYield 66.9%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Salicylaldehyde (15.2 g) and γ-valerolactone (25 g) were dissolved in toluene (150 ml). By the reactions as in the same manner as in Example 307, the title compound (17 g) was obtained, melting point 112-114° C.

Sources & evidence

ORD record
ord-d66337da2a3d4733bf336a925103d00a
Source dataset
uspto-grants-2004_04
Patent number
US06720320B2

Reaction notes

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