Propargyl bromide → 4,9-Dihydro-3-methyl-4-(prop-2-ynyl)-10H-thieno[3,4-b][1,5]benzodiazepin-10-one
Reaction equation
[Br:17][CH2:18][C:19]#[CH:20].[CH3:1][c:2]1[s:3][cH:4][c:5]2[c:6]1[NH:7][c:8]1[c:9]([cH:13][cH:14][cH:15][cH:16]1)[NH:10][C:11]2=[O:12].[Li:21][CH2:22][CH2:23][CH2:24][CH3:25].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[CH3:1][c:2]1[s:3][cH:4][c:5]2[c:6]1[N:7]([CH2:20][C:19]#[CH:18])[c:8]1[c:9]([cH:13][cH:14][cH:15][cH:16]1)[NH:10][C:11]2=[O:12]Participants
5
Sources & evidence
- ORD record
- ord-ea934a1bac2e4db0aad3ef3fe3762820
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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