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HRID2085473

反应详情

EQUATION

反应方程式

HRID 2085473 的结构方程式

REACTANTS

反应物

2
结构：CN(C)C1(CN)CCCC1
HCID10844493

1-(Aminomethyl)-N,N-dimethylcyclopentan-1-amine

C8H18N2

结构：Nc1nc(Nc2ccc(C(=O)O)cc2)sc1C(=O)c1c(F)cccc1F
HCID11257352

4-[4-Amino-5-(2,6-difluoro-benzoyl)-thiazol-2-ylamino]-benzoic Acid

C17H11F2N3O3S

PRODUCTS

生成物

1
结构：CN(C)C1(CNC(=O)c2ccc(Nc3nc(N)c(C(=O)c4c(F)cccc4F)s3)cc2)CCCC1
HCID22731063

未命名化合物

收率 62%

PROCEDURE

实验过程

The title compound was prepared in a manner similar to Step 3 in Method A; from coupling 4-[4-amino-5-(2,6-difluoro-benzoyl)-thiazol-2-ylamino]-benzoic acid (3) and 1-(aminomethyl)-N,N-dimethylcyclopentanamine (Yang et al., Eur. J. Med. Chem. 31, 231-239 (1996)) to afford a yellow amorphous powder in 62% yield.

WORKUP

后处理

  1. customto afford a yellow amorphous powder in 62% yield