N,N-Dimethylethylenediamine → HCID 10116666, compound

HRID 2085475Notes

Reaction equation

HRID 2085475 reaction equation
[NH2:1][C:2]1[N:3]=[C:4]([NH:17][C:18]2[CH:26]=[CH:25][C:21]([C:22](O)=[O:23])=[C:20]([Cl:27])[CH:19]=2)[S:5][C:6]=1[C:7](=[O:16])[C:8]1[C:13]([F:14])=[CH:12][CH:11]=[CH:10][C:9]=1[F:15].[CH3:28][N:29]([CH3:33])[CH2:30][CH2:31][NH2:32]>>[NH2:1][C:2]1[N:3]=[C:4]([NH:17][C:18]2[CH:26]=[CH:25][C:21]([C:22]([NH:32][CH2:31][CH2:30][N:29]([CH3:33])[CH3:28])=[O:23])=[C:20]([Cl:27])[CH:19]=2)[S:5][C:6]=1[C:7](=[O:16])[C:8]1[C:9]([F:15])=[CH:10][CH:11]=[CH:12][C:13]=1[F:14]

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 22730999HCID 22730999, compound

Product 1

HCID 10116666HCID 10116666, compound

Procedure

The title compound was prepared from 4-{4-amino-5-(2,6-difluoro-benzoyl)-thiazol-2-ylamino}-2-chloro-benzoic acid (12) and N,N-dimethyl-ethylene-diamine in a manner similar to Step 3 in Method A.

Sources & evidence

ORD record
ord-82996693dd2940fc81f0b9483bfd8e46
Source dataset
uspto-grants-2004_04
Patent number
US06720346B2

Reaction notes

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