HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylhistamine → HCID 10116086, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylhistamine | HCID 3614 | — |
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-Chloro-5-(2-chloroethyl)amino-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)benzamide | HCID 11417653 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 10116086 | HCID 10116086 | 16.2% |
Reaction Steps
Prepared as in Example 32 using 2-chloro-5-[(2-chloroethyl)amino]-N-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-benzamide (Example 29c, 0.200 g), 1-methylhistamine (0.400 g), N,N-diisopropylethylamine (1 ml), potassium iodide (0.080 g) and n-butanol (4 ml) to give the title compound as a gum (0.040 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06720452B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-c9640b5f3911429ca98c12c7751ac40c |
| Source note | uspto-grants-2004_04 |