HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2085940Generated: November 1, 2026
Dimethylamine → 6-(N,N-Dimethylamino)-3H-pyrido[3,4-d]pyrimidin-4-one
https://huagongshe.com/reaction/2085940
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 6-chloro-3H,4H-pyrido[3,4-d]pyrimidin-4-one | HCID 135480525 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-(N,N-Dimethylamino)-3H-pyrido[3,4-d]pyrimidin-4-one | HCID 135817446 | — |
Reaction Steps
Alternatively, 6-chloro-pyrido[3,4-d]pyrimidin-4-one (26.14 g) was treated with 2N dimethylamine in ethanol (200 ml) and heated at 130° C. in a Parr bomb for 3 days. The cooled mixture was filtered and triturated from isopropanol to give the title compound (16.61 g) as a yellow solid; m/z (M+1+) 191.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06723726B1 |
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| Source dataset | uspto-grants-2004_04 |
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| ORD ID | ord-191c335caac94d5bb70101d12843b288 |
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| Source note | uspto-grants-2004_04 |
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