HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 1-[3-(6-Bromo-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 22727951 | HCID 22727951 | — |
| Product | 1-[3-(6-Bromo-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]pyrrolidin-2-one | HCID 22727958 | — |
Reaction Steps
1-[3-(6-Bromo-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]pyrrolidin-2-one was prepared from 1-[3-(5-bromo-3-nitropyridin-2-ylamino)phenyl]pyrrolidin-2-one as described in Example 1. Oxalate salt, white crystals, m.p. 194-195° C. (from ethanol); δH (360 MHz, d6-DMSO) 2.10 (2H, quin, J 7), 2.56 (2H, t, J 8), 3.92 (2H, t, J 7), 7.58-7.65 (2H, m), 7.78-7.81 (1H, m), 8.19 (1H, s), 8.52-8.54 (2H, m), 8.93 (1H, s); m/z (ES+) 357 and 359 (M++H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06723735B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-73de8af29c9b47f193e6d6566901187b |
| Source note | uspto-grants-2004_04 |