反应详情

A solution of methyl 2-[[(benzyloxy)carbonyl]amino]-3-[(tert-butoxycarbonyl)amino]propanoate (4.3 g) in toluene (20 ml) was treated dropwise with trifluoroacetic acid (20 ml) and stirred at room temperature for 1 hour, and concentrated under reduced pressure. The residue was crystallized from ethyl acetate to obtain methyl 3-amino-2-[[(benzyloxy)carbonyl)amino]propanoate trifluoroacetate (4.4 g).

1. concentrationconcentrated under reduced pressure
2. customThe residue was crystallized from ethyl acetate