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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087129Generated: October 30, 2026

3-Bromopropylamine hydrobromide → tert-butyl N-(3-bromopropyl)carbamate

https://huagongshe.com/reaction/2087129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromopropylamine hydrobromideHCID 78701—
ReactantDi-tert-butyl dicarbonateHCID 90495—
SolventDichloromethaneHCID 6344—
Producttert-butyl N-(3-bromopropyl)carbamateHCID 4460490—

Reaction Steps

Prepared from 3-bromopropylamine hydrobromide and BOC2O in the presence of base in dichloromethane, 9.89 mmol: 1H NMR (CDCl3) δ 5.07 (br, 1H), 3.31 (t, 2H, J=6.6 Hz), 3.12 (apparent br q, 2H, J=6.0 Hz), 1.92 (p, 2H, J=6.6 Hz), 1.30 (s, 9H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-887ae971ac1143569bfedbd7fb3a8829
Source noteuspto-grants-2004_04