Potassium Carbonate → HCID 22049327, compound

HRID 2087268Notes

Reaction equation

HRID 2087268 reaction equation
C([O-])([O-])=O.[K+].[K+].Cl[CH2:8][CH2:9][C:10]([C:12]1[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=1)=[O:11].[CH3:19][CH:20]([CH3:36])[C:21]([NH:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[CH:25]=1)=[O:22]>>[F:18][C:15]1[CH:16]=[CH:17][C:12]([C:10](=[O:11])[CH2:9][CH2:8][N:33]2[CH2:34][CH2:35][CH:30]([C:26]3[CH:25]=[C:24]([NH:23][C:21](=[O:22])[CH:20]([CH3:19])[CH3:36])[CH:29]=[CH:28][CH:27]=3)[CH2:31][CH2:32]2)=[CH:13][CH:14]=1

Participants

4

Reactant 3

HCID 11430Potassium CarbonateHCID 676722-Chloro-4'-fluoropropiophenoneHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 22049327HCID 22049327, compound

Procedure

Procedure K (KI) and Scheme E (K2CO3) using 3-chloro-1-(4-fluorophenyl)-1-propanone and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 397.2 (M+H)+.

Sources & evidence

ORD record
ord-b098b9a3641f4cadbcf50dfd9ef465d1
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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