2,6-Dichlorophenol → HCID 22049468, compound

HRID 2087281Notes

Reaction equation

HRID 2087281 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([OH:29])[CH2:9][CH2:10][N:11]2[CH2:16][CH2:15][CH:14]([C:17]3[CH:18]=[C:19]([NH:23][C:24](=[O:28])[CH:25]([CH3:27])[CH3:26])[CH:20]=[CH:21][CH:22]=3)[CH2:13][CH2:12]2)=[CH:4][CH:3]=1.[Cl:30][C:31]1[CH:36]=[CH:35][CH:34]=[C:33]([Cl:37])[C:32]=1O>>[Cl:30][C:31]1[CH:36]=[CH:35][CH:34]=[C:33]([Cl:37])[C:32]=1[O:29][CH:8]([C:5]1[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=1)[CH2:9][CH2:10][N:11]1[CH2:16][CH2:15][CH:14]([C:17]2[CH:18]=[C:19]([NH:23][C:24](=[O:28])[CH:25]([CH3:26])[CH3:27])[CH:20]=[CH:21][CH:22]=2)[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 68992,6-DichlorophenolHCID 22049137HCID 22049137, compound

Product 1

HCID 22049468HCID 22049468, compound

Procedure

Prepared by Procedure A and Scheme AN using N-(3-{1-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 2,6-dichlorophenol: ESMS m/e: 543.0 (M+H)+.

Sources & evidence

ORD record
ord-20a9cbbda70945b9a3b7c243cb7321b1
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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