4-Chlorophenol → 1-Chloro-4-{[(2R)-3-chloro-2-methylpropyl]oxy}benzene

HRID 2087503Notes

Reaction equation

HRID 2087503 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.Br[CH2:10][C@@H:11]([CH3:14])[CH2:12][Cl:13]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:10][C@@H:11]([CH3:14])[CH2:12][Cl:13])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 46844-ChlorophenolHCID 5479122(2S)-1-bromo-3-chloro-2-methylpropane

Product 1

HCID 695243531-Chloro-4-{[(2R)-3-chloro-2-methylpropyl]oxy}benzene

Procedure

Prepared by Procedure U and Scheme AK using 4-chlorophenol and (2S)-1-bromo-3-chloro-2-methylpropane.

Workup

  1. customPrepared by Procedure U and Scheme AK

Sources & evidence

ORD record
ord-ee6149271a3543fcb5b8b0a25067a8a0
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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