Indole → 1-[2-(Trifluoromethyl)phenyl]-1H-indole

HRID 2087614Notes

Reaction equation

HRID 2087614 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.I[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[C:17]([F:20])([F:19])[F:18]>>[F:18][C:17]([F:20])([F:19])[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=1[N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1

Participants

3

Reactant 2

HCID 798IndoleHCID 67957Benzene, 1-iodo-2-(trifluoromethyl)-

Product 1

HCID 220496171-[2-(Trifluoromethyl)phenyl]-1H-indole

Procedure

Prepared by Procedure C and Scheme O using 1H-indole and 1-iodo-2-(trifluoromethyl)benzene: ESMS m/e: 262.0 (M+H)+.

Workup

  1. customPrepared by Procedure C and Scheme O

Sources & evidence

ORD record
ord-64f3bcd51318418eac14af2edaa46d0c
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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