P-Cresol → 5-(4-methylphenoxy)-1H-indole

HRID 2087658Notes

Reaction equation

HRID 2087658 reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[CH:5]2.[CH:11]1[C:16]([OH:17])=[CH:15][CH:14]=[C:13]([CH3:18])[CH:12]=1>>[CH3:18][C:13]1[CH:12]=[CH:11][C:16]([O:17][C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[NH:7][CH:6]=[CH:5]3)=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 2879P-CresolHCID 249055-Bromoindole

Product 1

HCID 220488355-(4-methylphenoxy)-1H-indole

Procedure

Prepared by Procedure J and Scheme U using 5-bromo-1H-indole and p-cresol: ESMS m/e: 224.0 (M+H)+.

Workup

  1. customPrepared by Procedure J and Scheme U

Sources & evidence

ORD record
ord-9707a40cd1ca40b9852d099040efea48
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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