5-(3,5-Dichlorophenoxy)furan-2-carbonyl chloride → HCID 22048741, compound

HRID 2087782Notes

Reaction equation

HRID 2087782 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][N:8]1[CH2:13][CH2:12][CH:11]([C:14]2[CH:15]=[C:16]([NH:20][C:21](=[O:25])[CH:22]([CH3:24])[CH3:23])[CH:17]=[CH:18][CH:19]=2)[CH2:10][CH2:9]1.[Cl:26][C:27]1[CH:28]=[C:29]([CH:39]=[C:40]([Cl:42])[CH:41]=1)[O:30][C:31]1[O:35][C:34]([C:36](Cl)=[O:37])=[CH:33][CH:32]=1>C1COCC1>[Cl:26][C:27]1[CH:28]=[C:29]([CH:39]=[C:40]([Cl:42])[CH:41]=1)[O:30][C:31]1[O:35][C:34]([C:36]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][N:8]2[CH2:13][CH2:12][CH:11]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([NH:20][C:21](=[O:25])[CH:22]([CH3:23])[CH3:24])[CH:15]=3)[CH2:10][CH2:9]2)=[O:37])=[CH:33][CH:32]=1

Participants

4

Reactant 2

HCID 27360285-(3,5-Dichlorophenoxy)furan-2-carbonyl chlorideHCID 16755868N-{3-[1-(6-Aminohexyl)4-piperidinyl]phenyl}-2-methylpropanamide

Product 1

HCID 22048741HCID 22048741, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(6-aminohexyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 5-(3,5-dichlorophenoxy)-2-furoyl chloride: ESMS m/e: 600.2 (M+H)+.

Sources & evidence

ORD record
ord-094ae194d3764c6e87e47eb69a09b010
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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