3,4-Dimethoxybenzenesulfonyl chloride → HCID 22048641, compound

HRID 2087793Notes

Reaction equation

HRID 2087793 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][CH:8]([C:11]2[CH:12]=[C:13]([NH:17][C:18](=[O:22])[CH:19]([CH3:21])[CH3:20])[CH:14]=[CH:15][CH:16]=2)[CH2:7][CH2:6]1.[CH3:23][O:24][C:25]1[CH:26]=[C:27]([S:33](Cl)(=[O:35])=[O:34])[CH:28]=[CH:29][C:30]=1[O:31][CH3:32]>C1COCC1>[CH3:23][O:24][C:25]1[CH:26]=[C:27]([S:33]([NH:1][CH2:2][CH2:3][CH2:4][N:5]2[CH2:10][CH2:9][CH:8]([C:11]3[CH:12]=[C:13]([NH:17][C:18](=[O:22])[CH:19]([CH3:20])[CH3:21])[CH:14]=[CH:15][CH:16]=3)[CH2:7][CH2:6]2)(=[O:34])=[O:35])[CH:28]=[CH:29][C:30]=1[O:31][CH3:32]

Participants

4

Reactant 2

HCID 27341833,4-Dimethoxybenzenesulfonyl chlorideHCID 16757470N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}2-methylpropanamide

Product 1

HCID 22048641HCID 22048641, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3,4-dimethoxybenzenesulfonyl chloride: ESMS m/e: 504.2 (M+H)+.

Sources & evidence

ORD record
ord-e91b2cb70f4a4f41b9c5de0e8e34096f
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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