HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Chlorophenoxy)pyridine-3-carbonyl chloride → 2-(4-Chlorophenoxy)-N-(3-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}propyl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Chlorophenoxy)pyridine-3-carbonyl chloride | HCID 2774898 | — |
| Reactant | N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}2-methylpropanamide | HCID 16757470 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(4-Chlorophenoxy)-N-(3-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}propyl)nicotinamide | HCID 22048915 | — |
Reaction Steps
Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(3-aminopropyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 2-(4-chlorophenoxy)nicotinoyl chloride: ESMS m/e: 535.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727264B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-bf0391bf22804dc6bd60643c495e4eb1 |
| Source note | uspto-grants-2004_04 |