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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087806Generated: November 2, 2026

2-Naphthoyl chloride → N-(2-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}ethyl)-2-naphthamide

https://huagongshe.com/reaction/2087806

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Naphthoyl chlorideHCID 75246—
ReactantN-(3-[1-(2-aminoethyl)-4-piperidinyl]phenyl)-2-methylpropanamideHCID 16757469—
SolventTetrahydrofuranHCID 8028—
ProductN-(2-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}ethyl)-2-naphthamideHCID 22048924—

Reaction Steps

Prepared by Procedure Q1 (THF) and Scheme AT using N-(3-[1-(2-aminoethyl)-4-piperidinyl]phenyl)-2-methylpropanamide and 2-naphthoyl chloride: ESMS m/e: 444. 2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-a65d88279ee9425fb2ff5113f5f2066e
Source noteuspto-grants-2004_04