HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride → 3-(2,6-Dichlorophenyl)-N-(5-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}pentyl)-5-methyl-4-isoxazolecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride | HCID 78212 | — |
| Reactant | N-{3-[1-(5-aminopentyl)-4-piperidinyl]phenyl}-2-methylpropanamide | HCID 16755867 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(2,6-Dichlorophenyl)-N-(5-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}pentyl)-5-methyl-4-isoxazolecarboxamide | HCID 22048723 | — |
Reaction Steps
Prepared by Procedure Q1 (THF) and Scheme AT using N-{3-[1-(5-aminopentyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride. ESMS m/e: 585.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727264B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-b59e5ca87f8f42e69b57e7d4879e865c |
| Source note | uspto-grants-2004_04 |