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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2088317Generated: November 3, 2026

5-(trifluoromethyl)pyridine-2-carboxylic Acid → HCID 59331162, compound

https://huagongshe.com/reaction/2088317

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(trifluoromethyl)pyridine-2-carboxylic AcidHCID 10910349—
ReactantHCID 44286533HCID 44286533—
ProductHCID 59331162HCID 59331162—

Reaction Steps

Title compound was synthesized according to the procedure used in the synthesis of Compound 19S, using 5-(trifluoromethyl)picolinic acid in place of o-methoxybenzoic acid. 1H NMR (400 MHz, CDCl3) δ (ppm): 8.98 (s, 1H), 8.22 (dd, J=8 Hz, 1H), 7.71 (d, J=8 Hz, 1H), 6.36 (s, 1H), 4.11 (m, 1H), 3.39 (dd, J=16 Hz, 1H), 2.83-2.77 (m, 4H), 2.56 (ddd, J=16 Hz, 1H), 2.00 (m, 1H), 1.66 (m, 3H), 1.50 (m, 1H). C14H16F3N3O=299.12 LCMS (M+H): m/z 300

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08435762B2
Source datasetuspto-grants-2013_05
ORD IDord-2125a0946204422fb05df74e00bee6c7
Source noteuspto-grants-2013_05