反应详情

The title compound was prepared according to the procedures of Examples 1E and 1F, substituting the product from Example 9C for the product from Example 1D and substituting (R)-tert-butylmethyl(pyrrolidin-3-yl)carbamate for (R)-tert-butyl pyrrolidin-3-ylcarbamate. 1H NMR (300 MHz, CDCl3) δ 7.24 (m, 2H), 7.16 (t, J=7.29 Hz, 1H), 7.07 (d, J=7.12 Hz, 2H), 4.53 (s, 2H), 3.96 (t, J=6.27 Hz, 1H), 3.74 (m, 3H), 3.47 (m, 1H), 3.29 (m, 1H), 2.73 (m, 2H), 2.49 (d, J=2.71 Hz, 3H), 2.14 (m, 2H), 1.80 (m, 4H). MS (ESI+) m/z 324 (M+H)+.