Chlorotrimethylsilane → Tert-butyl 4-{4-[(trimethylsilyl)ethynyl]-1,3-thiazol-2-yl}piperidine-1-carboxylate
Reaction equation
[C:1](#[CH:2])[c:3]1[n:4][c:5]([CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[s:6][cH:7]1.[CH3:21][Si:22]([CH3:23])([CH3:24])[Cl:25].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[C:1](#[C:2][Si:22]([CH3:21])([CH3:23])[CH3:24])[c:3]1[n:4][c:5]([CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]2)[s:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-81454f2d6b7b4a4295db16b332266f6e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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