HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → 1H-indazol-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 1H-Indazole | HCID 9221 | — |
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1H-indazol-3-amine | HCID 13399 | — |
Reaction Steps
Indazole (XV) is treated with hydrazine in an organic solvent such as THF, dioxane or dichloromethane, at a temperature in the range of about 0° C. to about 25° C., to yield the corresponding indazole (IV).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436023B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-51eaac6dea544179a10339e7b1ceb214 |
| Source note | uspto-grants-2013_05 |