HuagongsheHuagongshe Chemistry Print Report · For research reference only
AGN-PC-0ND25R → N-[1-(4-Benzo[1,3]dioxol-5-yl-cyclohexyl)-azetidin-3-yl]-2-(5-trifluoromethoxy-benzo[d]isoxazol-3-ylamino)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | AGN-PC-0ND25R | HCID 10932904 | — |
| Reactant | N-azetidin-3-yl-2-(5-trifluoromethoxy-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt | HCID 86660177 | — |
| Product | N-[1-(4-Benzo[1,3]dioxol-5-yl-cyclohexyl)-azetidin-3-yl]-2-(5-trifluoromethoxy-benzo[d]isoxazol-3-ylamino)-acetamide | HCID 58548851 | — |
Reaction Steps
The title compound was prepared as a white solid from reaction of N-azetidin-3-yl-2-(5-trifluoromethoxy-benzo[d]isoxazol-3-ylamino)-acetamide TFA salt (as prepared in Example 1, Step D) and 4-benzo[1,3]dioxol-5-yl-cyclohexanone using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436023B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-3e68efb7a0ff479bb3335c0e65f83d07 |
| Source note | uspto-grants-2013_05 |