HuagongsheHuagongshe Chemistry Print Report · For research reference only
AGN-PC-0ND25R → N-[1-(4-Benzo[1,3]dioxol-5-yl-cyclohexyl)-azetidin-3-yl]-2-[1-(2-hydroxy-ethyl)-5-trifluoromethyl-1H-indazol-3-ylamino]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | AGN-PC-0ND25R | HCID 10932904 | — |
| Reactant | HCID 86660184 | HCID 86660184 | — |
| Product | N-[1-(4-Benzo[1,3]dioxol-5-yl-cyclohexyl)-azetidin-3-yl]-2-[1-(2-hydroxy-ethyl)-5-trifluoromethyl-1H-indazol-3-ylamino]-acetamide | HCID 54755801 | — |
Reaction Steps
The title compound was prepared as a white solid from reaction of N-azetidin-3-yl-2-[1-(2-hydroxy-ethyl)-5-trifluoromethyl-1H-indazol-3-ylamino]-acetamide TFA salt (as prepared in Example 74, Step A) and 4-benzo[1,3]dioxol-5-yl-cyclohexanone using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436023B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-e79a552cab2440c293a6a0604677fd8a |
| Source note | uspto-grants-2013_05 |