化工社化工社 化学情報印刷レポート · 研究参考用
Phthalic Anhydride → 2-(5-Trifluoromethyl-1H-indazol-3-yl)-isoindole-1,3-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phthalic Anhydride | HCID 6811 | — |
| 反応物 | Bay-H-1127 | HCID 16736 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 2-(5-Trifluoromethyl-1H-indazol-3-yl)-isoindole-1,3-dione | HCID 58548862 | — |
反応手順
Isobenzofuran-1,3-dione (4.24 g, 28.6 mmol) and 5-trifluoromethyl-1H-indazol-3-ylamine (5.76 g, 28.6 mmol) in dioxane (10 mL) in a sealed tube were heated at 100° C. overnight. The solvent was removed to give the crude product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08436023B2 |
| 出典データセット | uspto-grants-2013_05 |
| ORD ID | ord-1754c6b4a921448496e0b5417213958d |
| 出典メモ | uspto-grants-2013_05 |