HRID2089226

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID78605

4-Phenylcyclohexanone

C12H14O

结构：CC(C)NC(=O)n1nc(NCC(=O)NC2CNC2)c2cc(C(F)(F)F)ccc21

HCID58548858

未命名化合物

PRODUCTS

生成物

结构：CC(C)NC(=O)n1nc(NCC(=O)NC2CN(C3CCC(c4ccccc4)CC3)C2)c2cc(C(F)(F)F)ccc21

HCID54755924

未命名化合物

PROCEDURE

实验过程

The title compound was prepared as a white solid from reaction of 3-[(azetidin-3-ylcarbamoylmethyl)-amino]-5-trifluoromethyl-indazole-1-carboxylic acid isopropylamide and 4-phenyl-cyclohexanone using the procedure described in Step E of Example 1.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bd8331310e454bb880cfaefa2238f5ea
来源数据集: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08436023B2
来源说明: uspto-grants-2013_05

反应 SMILES

[CH:1]([NH:4][C:5]([N:7]1[C:15]2[C:10](=[CH:11][C:12]([C:16]([F:19])([F:18])[F:17])=[CH:13][CH:14]=2)[C:9]([NH:20][CH2:21][C:22](=[O:28])[NH:23][CH:24]2[CH2:27][NH:26][CH2:25]2)=[N:8]1)=[O:6])([CH3:3])[CH3:2].[C:29]1([CH:35]2[CH2:40][CH2:39][C:38](=O)[CH2:37][CH2:36]2)[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[CH:1]([NH:4][C:5]([N:7]1[C:15]2[C:10](=[CH:11][C:12]([C:16]([F:18])([F:19])[F:17])=[CH:13][CH:14]=2)[C:9]([NH:20][CH2:21][C:22](=[O:28])[NH:23][CH:24]2[CH2:25][N:26]([CH:38]3[CH2:37][CH2:36][CH:35]([C:29]4[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=4)[CH2:40][CH2:39]3)[CH2:27]2)=[N:8]1)=[O:6])([CH3:3])[CH3:2]