HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Isopropylcyclohexanone → 3-({[1-(4-Isopropyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-amino)-5-trifluoromethyl-indazole-1-carboxylic acid isopropylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Isopropylcyclohexanone | HCID 79488 | — |
| Reactant | 3-[(Azetidin-3-ylcarbamoylmethyl)-amino]-5-trifluoromethyl-indazole-1-carboxylic acid isopropylamide | HCID 58548858 | — |
| Product | 3-({[1-(4-Isopropyl-cyclohexyl)-azetidin-3-ylcarbamoyl]-methyl}-amino)-5-trifluoromethyl-indazole-1-carboxylic acid isopropylamide | HCID 54756042 | — |
Reaction Steps
The title compound was prepared as a white solid from reaction of 3-[(azetidin-3-ylcarbamoylmethyl)-amino]-5-trifluoromethyl-indazole-1-carboxylic acid isopropylamide (as prepared in Example 90, Step A) and 4-iso-propyl-cyclohexanone using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436023B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-9bb86a2fd87a42eaadbb207918a0c0ff |
| Source note | uspto-grants-2013_05 |