HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1,1'-Bicyclohexyl)-4-one → 3-{[(1-Bicyclohexyl-4-yl-azetidin-3-ylcarbamoyl)-methyl]-amino}-5-trifluoromethyl-indazole-1-carboxylic acid isopropylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1,1'-Bicyclohexyl)-4-one | HCID 41690 | — |
| Reactant | 3-[(Azetidin-3-ylcarbamoylmethyl)-amino]-5-trifluoromethyl-indazole-1-carboxylic acid isopropylamide | HCID 58548858 | — |
| Product | 3-{[(1-Bicyclohexyl-4-yl-azetidin-3-ylcarbamoyl)-methyl]-amino}-5-trifluoromethyl-indazole-1-carboxylic acid isopropylamide | HCID 54756044 | — |
Reaction Steps
The title compound was prepared as a white solid from reaction of 3-[(azetidin-3-ylcarbamoylmethyl)-amino]-5-trifluoromethyl-indazole-1-carboxylic acid isopropylamide (as prepared in Example 90, Step A) and bicyclohexyl-4-one using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436023B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-7894da8f7f864c50949cb2d17473e844 |
| Source note | uspto-grants-2013_05 |