HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(6-Methoxypyridin-3-yl)cyclohexanone → 2-(1-Methanesulfonyl-5-trifluoromethyl-1H-indazol-3-ylamino)-N-{1-[4-(6-methoxy-pyridin-3-yl)-cyclohexyl]-azetidin-3-yl}-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(6-Methoxypyridin-3-yl)cyclohexanone | HCID 67478868 | — |
| Reactant | N-azetidin-3-yl-2-(1-methanesulfonyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetamide TFA salt | HCID 86660185 | — |
| Product | 2-(1-Methanesulfonyl-5-trifluoromethyl-1H-indazol-3-ylamino)-N-{1-[4-(6-methoxy-pyridin-3-yl)-cyclohexyl]-azetidin-3-yl}-acetamide | HCID 67478769 | — |
Reaction Steps
The title compound was prepared as a white solid from reaction of N-azetidin-3-yl-2-(1-methanesulfonyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetamide TFA salt and 4-(6-methoxy-pyridin-3-yl)-cyclohexanone using the procedure described in Step E of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436023B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-1a5a82a7f4d742aaa050c7e9fa32ba54 |
| Source note | uspto-grants-2013_05 |