Hydrochloric Acid → HCID 14062559, compound

HRID 2089271Notes

Reaction equation

HRID 2089271 reaction equation
C(OC([C:6]1[N:10]([OH:11])[C:9]2[CH:12]=[C:13]([N+:16]([O-:18])=[O:17])[CH:14]=[CH:15][C:8]=2[N:7]=1)=O)C.[ClH:19]>>[ClH:19].[N+:16]([C:13]1[CH:14]=[CH:15][C:8]2[N:7]=[CH:6][N:10]([OH:11])[C:9]=2[CH:12]=1)([O-:18])=[O:17]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 10243868Ethyl 1-hydroxy-6-nitro-1H-benzimidazole-2-carboxylate

Product 1

HCID 14062559HCID 14062559, compound

Procedure

A mixture of 1-hydroxy-6-nitro-1H-benzoimidazole-2-carboxylic acid ethyl ester (3) (5 g, 20 mmol) and concentrated HCl (100 mL) was refluxed for 3 hours. After cooling the mixture to room temperature, the resulting solid was collected by filtration. Yield 1.9 g (44%) of the HCl salt.

Workup

  1. temperaturewas refluxed for 3 hours
  2. filtrationthe resulting solid was collected by filtration

Sources & evidence

ORD record
ord-4eb52b10c07a481f99185a939a38ad4c
Source dataset
uspto-grants-2013_05
Patent number
US08436031B2

Reaction notes

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