1-Methylpiperazine → HCID 58464829, compound

HRID 2089410Notes

Reaction equation

HRID 2089410 reaction equation
Cl[C:2]1[N:6]([CH3:7])[N:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].[CH3:11][N:12]1[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]1>>[CH3:11][N:12]1[CH2:17][CH2:16][N:15]([C:2]2[N:6]([CH3:7])[N:5]=[CH:4][C:3]=2[N+:8]([O-:10])=[O:9])[CH2:14][CH2:13]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 123448365-chloro-1-methyl-4-nitro-1H-pyrazole

Product 1

HCID 58464829HCID 58464829, compoundYield 65%

Procedure

Reaction of 5-chloro-1-methyl-4-nitro-1H-pyrazole and N-methyl piperazine gave 1-methyl-4-(1-methyl-4-nitro-1H-pyrazol-5-yl)piperazine as an oil (0.18 g, 65%). 1H NMR (400 MHz, CDCl3) δ 8.02 (s, 1H), 3.77 (s, 3H), 3.26 (t, J=4.6 Hz, 4H), 2.60-2.53 (m, 4H), 2.38 (s, 3H)

Sources & evidence

ORD record
ord-7fcfa4668f03429090743b44c43fd097
Source dataset
uspto-grants-2013_05
Patent number
US08436001B2

Reaction notes

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