HCID 59199399, compound → HCID 59199428, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of [3-(2,2-dimethyl-indan-1-yl)-3H-imidazol-4-yl]-methanol (120 mg, 0.5 mmol), which can be prepared as described in Example 23, in 1,4-dioxane (5 mL) is added manganese (IV) oxide (434 mg, 5 mmol). The reaction is then heated at 90° C. for 1 hour, at which time the reaction is cooled to room temperature and filtered to furnish 3-(2,2-dimethyl-indan-1-yl)-3H-imidazole-4-carbaldehyde without the need for further purification; MS: (ESI) m/z 241.1 (M+H)+.

Provenance & Evidence