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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2089595Generated: October 30, 2026

Tetrahydro-4H-pyran-4-one → (Tetrahydropyran-4-yl)-(5-chloro-3-phenyl-1H-indol-7-yl)-amine

https://huagongshe.com/reaction/2089595

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydro-4H-pyran-4-oneHCID 121599—
Reactant5-Chloro-3-phenyl-7-nitro-1H-indoleHCID 68471840—
Product(Tetrahydropyran-4-yl)-(5-chloro-3-phenyl-1H-indol-7-yl)-amineHCID 25215218—

Reaction Steps

5-Chloro-7-nitro-3-phenyl-1H-indole prepared in Preparation 41 and tetrahydropyran-4-one were reacted according to the same procedure as Example 1 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08436038B2
Source datasetuspto-grants-2013_05
ORD IDord-c39072c89d61434eb6506e554cb4808b
Source noteuspto-grants-2013_05