Methyl bromoacetate → HCID 68476525, compound

HRID 2089611Notes

Reaction equation

HRID 2089611 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([F:19])[CH:7]=[C:8]2[C:12]=1[NH:11][C:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[CH:9]2)([O-])=O.Br[CH2:21][C:22]([O:24][CH3:25])=[O:23]>>[CH3:25][O:24][C:22](=[O:23])[CH2:21][NH:1][C:4]1[CH:5]=[C:6]([F:19])[CH:7]=[C:8]2[C:12]=1[NH:11][C:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[CH:9]2

Participants

3

Reactant 2

HCID 60984Methyl bromoacetateHCID 68474032HCID 68474032, compound

Product 1

HCID 68476525HCID 68476525, compound

Procedure

7-Nitro-5-fluoro-2-phenyl-1H-indole prepared in Preparation 27 and methyl bromoacetate were reacted according to the same procedures as Step A of Example 1 and Example 22 sequentially to give the title compound.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-d53d378e8f1542928a024d043bb41805
Source dataset
uspto-grants-2013_05
Patent number
US08436038B2

Reaction notes

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