m-Chloroperbenzoic acid → 3-(2-Butyl-5-oxido-1H-imidazo[4,5-c]quinolin-1-yl)propyl pentanoate

Participants

Reaction Steps

3-Chloroperoxybenzoic acid (1.6 g) was added to a solution of the product from step (iii) (2.15 g) in DCM (30 mL) at 5° C. The reaction mixture was allowed to warm to rt, stirred for 18 h and partitioned between DCM/saturated sodium bisulfate solution. The organics were separated washed with saturated NaHCO3 solution, water, dried and evaporated under reduced pressure. Yield 1.77 g

Provenance & Evidence