HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2090247Generated: November 1, 2026
1-Methyl-4-piperidone → HCID 68432258, compound
https://huagongshe.com/reaction/2090247
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 1-(3-aminopropyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine | HCID 22344413 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 68432258 | HCID 68432258 | — |
Reaction Steps
Sodium triacetoxyborohydride (1.07 g) was added to a stirred mixture of the product from example 1 step (vii) (502 mg) and 1-methylpiperidin-4-one (0.21 mL) in NMP (2 mL) at rt. The resulting solution was stirred at 50° C. for 3 h, then purified by SCX, yield 335 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08436178B2 |
|---|
| Source dataset | uspto-grants-2013_05 |
|---|
| ORD ID | ord-d823c63b6a4c443a877a403f80b6d0f4 |
|---|
| Source note | uspto-grants-2013_05 |
|---|
