HRID2090260

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID53167

1-Methylpiperazine

C5H12N2

结构：CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(CCCN(C)C)Cc1cccc(CC(=O)OC)c1

HCID59563517

未命名化合物

PRODUCTS

生成物

结构：CCCCc1nc2c(N)nc3ccccc3c2n1CCCN(CCCN1CCN(C)CC1)Cc1cccc(CC(=O)OC)c1

HCID25106783

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by the method of example 11step (x) using the product of example11 step (ix) (627 mg) and N-methylpiperazine (1 ml) as a colourless gum 120 mg.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-dbe11c4d43a14adfaa7576040951dbd8
来源数据集: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08436178B2
来源说明: uspto-grants-2013_05

反应 SMILES

[NH2:1][C:2]1[C:11]2[N:12]=[C:13]([CH2:37][CH2:38][CH2:39][CH3:40])[N:14]([CH2:15][CH2:16][CH2:17][N:18]([CH2:25][C:26]3[CH:27]=[C:28]([CH2:32][C:33]([O:35][CH3:36])=[O:34])[CH:29]=[CH:30][CH:31]=3)[CH2:19][CH2:20][CH2:21][N:22]([CH3:24])[CH3:23])[C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1.[CH3:41][N:42]1[CH2:47]CNC[CH2:43]1>>[NH2:1][C:2]1[C:11]2[N:12]=[C:13]([CH2:37][CH2:38][CH2:39][CH3:40])[N:14]([CH2:15][CH2:16][CH2:17][N:18]([CH2:25][C:26]3[CH:27]=[C:28]([CH2:32][C:33]([O:35][CH3:36])=[O:34])[CH:29]=[CH:30][CH:31]=3)[CH2:19][CH2:20][CH2:21][N:22]3[CH2:23][CH2:43][N:42]([CH3:47])[CH2:41][CH2:24]3)[C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1