1-Methylpiperazine → HCID 25106783, compound

HRID 2090260Notes

Reaction equation

[NH2:1][C:2]1[C:11]2[N:12]=[C:13]([CH2:37][CH2:38][CH2:39][CH3:40])[N:14]([CH2:15][CH2:16][CH2:17][N:18]([CH2:25][C:26]3[CH:27]=[C:28]([CH2:32][C:33]([O:35][CH3:36])=[O:34])[CH:29]=[CH:30][CH:31]=3)[CH2:19][CH2:20][CH2:21][N:22]([CH3:24])[CH3:23])[C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1.[CH3:41][N:42]1[CH2:47]CNC[CH2:43]1>>[NH2:1][C:2]1[C:11]2[N:12]=[C:13]([CH2:37][CH2:38][CH2:39][CH3:40])[N:14]([CH2:15][CH2:16][CH2:17][N:18]([CH2:25][C:26]3[CH:27]=[C:28]([CH2:32][C:33]([O:35][CH3:36])=[O:34])[CH:29]=[CH:30][CH:31]=3)[CH2:19][CH2:20][CH2:21][N:22]3[CH2:23][CH2:43][N:42]([CH3:47])[CH2:41][CH2:24]3)[C:10]=2[C:9]2[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=2[N:3]=1

Participants

Reactant 2

HCID 531671-Methylpiperazine

HCID 59563517HCID 59563517, compound

Product 1

HCID 25106783HCID 25106783, compound

Procedure

The title compound was prepared by the method of example 11step (x) using the product of example11 step (ix) (627 mg) and N-methylpiperazine (1 ml) as a colourless gum 120 mg.

Sources & evidence

ORD record: ord-dbe11c4d43a14adfaa7576040951dbd8
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08436178B2

Reaction notes

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