HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-hydroxybenzonitrile → HCID 46701320, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-hydroxybenzonitrile | HCID 592797 | — |
| Reactant | 4-(7-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine | HCID 46701048 | — |
| Product | HCID 46701320 | HCID 46701320 | — |
Reaction Steps
This compound was prepared by using procedures analogous to those described for the synthesis of Example 17 starting from 4-(7-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine and 2-chloro-4-hydroxybenzonitrile (Aldrich, Cat. No. 346071). LCMS (M+H)+: m/z=476.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436008B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-becbfede63b5494a9f51aa9a408d7004 |
| Source note | uspto-grants-2013_05 |